30 octombrie 2021
Sâm, 30.10
17:30
PSV Eindhoven
PSV Eindhoven
5
Twente
Twente
2
Sâm, 30.10
19:45
Heracles
Heracles
0
Ajax
Ajax
0
Sâm, 30.10
21:00
SC Heerenveen
SC Heerenveen
1
Vitesse
Vitesse
2
Sâm, 30.10
22:00
Alkmaar
Alkmaar
3
PEC Zwolle
PEC Zwolle
2
31 octombrie 2021
Dum, 31.10
13:15
Sparta Rotterdam
Sparta Rotterdam
0
Feyenoord
Feyenoord
1
Dum, 31.10
15:30
NEC Nijmegen
NEC Nijmegen
3
FC Groningen
FC Groningen
0
Dum, 31.10
17:45
FC Utrecht
FC Utrecht
5
Willem
Willem
1
Dum, 31.10
17:45
RKC Waalwijk
RKC Waalwijk
0
Cambuur
Cambuur
1
Dum, 31.10
21:00
Go Ahead Eagles
Go Ahead Eagles
4
Fortuna Sittard
Fortuna Sittard
3
Etapa anterioară Etapa următoare